- Among people with kidney failure who received dialysis at clinics several times a week, the risks of COVID-19 were higher in older patients with diabetes living in local communities with COVID rates -19 higher and having received dialysis in clinics that served a greater number of patients.
- Risks were lower in patients who received dialysis at clinics with a greater number of available side chambers and who had mask policies for asymptomatic patients.
Washington, DC (June 1, 2021) – Many people with kidney failure have been unable to self-isolate during the COVID-19 pandemic because they require dialysis treatments in clinics several times a week. New research that will appear in a future issue of CJASN highlights the risks run by these patients and the factors involved.
For the study, Ben Caplin, MBChB, PhD (University College London) and colleagues, on behalf of the Pan-London COVID-19 Renal Audit Group, reviewed information on 5,755 patients who received dialysis at 51 clinics in London. Between March 2 and May 31, 2020, a total of 990 (17%) patients tested positive and 465 (8%) were admitted to hospitals on suspicion of COVID-19. The risks of COVID-19 were higher in older patients with diabetes, living in local communities with higher rates of COVID-19, and who received dialysis at dialysis clinics that served a greater number of patients. Risks were lower in patients who received dialysis at clinics with a greater number of available side chambers and who had mask policies for asymptomatic patients. No independent association was observed with gender, ethnicity or deprivation measures.
“Taken together, the results confirm the high rates of symptomatic COVID-19 in patients receiving on-center dialysis and suggest sources of transmission both within the dialysis units and in the communities of origin of patients,” said Dr. Caplin. “The work also suggests that in addition to isolating confirmed cases, addressing factors that could reduce transmission from patients without suspected or confirmed disease could offer an additional opportunity to further modify the impact of COVID-19. in this population. ”
Study co-authors include Damien Ashby, Kieran McCafferty, Richard Hull, Elham Asgari, Martin L. Ford, Nicholas Cole, Marilina Antonelou, Sarah A. Blakey, Vinay Srinivasa, Dandisonba CB Braide-Azikwe, Tayeba Roper, Grace Clark, Helen Cronin, Nathan J. Hayes, Bethia Manson, Alexander Sarnowski, Richard Corbett, Kate Bramham, Eirini Lioudak7, Nicola Kumar, Andrew Frankel, David Makanjuola, Claire C. Sharpe, Debasish Banerjee and Alan D. Salama.
Disclosures: Dr Caplin reports Lifearc personal expenses, Astra Zeneca grants, Colt Foundation grants, Medical Research Council grants, Royal Free Charity, outside of submitted work; Dr Ashby reports personal costs for Fibrogen, outside of submitted work; Dr Corbett is the holder of a patent WO2017148836A1: “A device for maintaining vascular connections” issued; Dr Banerjee reports grants from AstraZeneca, grants from Kidney Research UK, personal fees from ViforPharma, outside of submitted work.
The article, titled “Risk of COVID-19 Disease, Dialysis Unit Attributes, and Infection Control Strategy Among London In-Center Hemodialysis Patients”, will appear online at http: // cjasn.
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